Based upon an attentive reading of Nietzsche’s writings and his reception among post-Nietzschean thinkers, this book argues that Nietzsche’s philosophical enterprise constitutes a materialist metaphysics of pure becoming, of pure immanence and the power of the virtual.

Grigorieff showed that forcing to add a subset of ω using partial functions with suitably chosen domains can add a generic real of minimal degree. We show that forcing with partial functions to add a subset of an uncountable κ without adding a real never adds a generic of minimal degree. This is in contrast to forcing using branching conditions, as shown by Brown and Groszek.

We show, for each computable ordinal α and degree $\alpha > {0^{\left( \alpha \right)}}$, the existence of a torsion-free abelian group with proper α th jump degree α.

During the late nineties, leading voices of the sex worker rights movement began to publicly question queer theory’s virtual silence on the subject of prostitution and sex work. However, this attempt by sex workers to “come out of the closet” into the larger queer theoretical community has thus far failed to bring much attention to sex work as an explicitly queer issue. Refusing the obvious conclusion—that queer theory’s silence on sex work somehow proves its insignificance to this field of inquiry—I (...) trace in Foucault’s oeuvre signs of an alternate queer genealogy of prostitution and sex work. Both challenging and responding to long-standing debates about prostitution within feminist theory, I offer a new queer genealogy of sex work that aims to move beyond the rigid oppositions that continue to divide theorists of sexuality and gender. Focusing specifically on History of Madness, Discipline and Punish, and History of Sexuality Volume I, I make the case for an alternate genealogy of sex work that takes seriously both the historical construction of prostitution and the lived experience of contemporary sex workers. (shrink)

In opposition to any notion of poverty as privation, or ‘bare life’, Negrian discourse poses the problem of poverty as a precondition for innovation and self-constitution, that is, for the critical appropriation of the immeasurable. This appropriation, as depicted in Kairòs, Alma Venus, and Multitudo, occurs in the event of adequation, when the monstrous store of potentia (immanent to poverty) exposes itself to the void in the projection of the ‘to-come’. This essay seeks in turn to resolve a series of (...) vexing questions and problems concerning the function of poverty, love, and the monstrous in the Negrian constitution of reality. (shrink)

The solution structures of several small proteins have recently been determined from high‐resolution nuclear magnetic resonance data. The principal features of the methods available to do this are outlined here, together with the advantages, limitations and future prospects of the technique.

The human major histocompatibility complex (MHC), on the short arm of chromosome 6, represents one of the most extensively characterised regions of the human genome. This ∼4 Mb segment of DNA contains genes encoding the polymorphic MHC class I and class II molecules which are involved in antigen presentation during an immune response. Recently the whole of the MHC has been cloned in cosmids and/or yeast artificial chromosomes (YACs) and large portions have been characterised for the presence of novel genes. (...) Many unrelated genes, both housekeeping and tissue specific, have been identified and the gene density in some regions is now approaching one gene every few kilobases. Some of the novel genes encode proteins involved in the intracellular processing and transport of antigens that are presented by MHC class I molecules. Others, however, have no obvious role in the immune response. The MHC is located in the chromosome band 6p21.3 which is a Giemsa (G)‐light band. The detection of such a large number of functional genes (at least 70) in this region is compatible with the idea that both housekeeping and tissue‐specific genes are localised predominantly in G‐light bands. (shrink)

Over the last 20 years, sex offender policies, specifically in terms of community corrections, have increased in scope. One of the most controversial and pervasive sex offender policies is that of registration. In response to the consumption of already limited resources, jurisdictions have imposed increasingly higher community supervision fees onto the offenders, requiring them to pay for their own re-entry. However, to date no research study has examined the statutory language associated with registration fees collected post release from formal community (...) sanctions. Using a statutory analysis within the United States, this research finds and quantifies the imposition of a registration fee on offenders who are legally compelled to pay these registration costs, regardless of whether they are still currently under community supervision. Results show that more than half of U.S. states (n = 28) incorporate statutory language authorizing registration fees, ranging anywhere from $5 per registration to up to $250 per year. These findings, as well as suggestions for future research and policy recommendations, are discussed. (shrink)

The difficulty of τєἠν at 8 is notorious, and it has never been answered. The word refers back to Apollo, who has been invoked in the first line, but ‘it is not in accord with epic convention that, after the invocation, reference should be made to it’. I suggest that we simply should not expect Apollonius to conform to the conventions of older epic: he does not do so in a number of other important respects. One is reminded here of (...) the nervous restlessness of Callimachean poetry, particularly Cer. 25. There the goddess is addressed out of the blue with τìν δ’ αύτᾳ, and emendation is unconvincing. Perhaps τєἠν in Apollonius is even more abrupt than the example in Callimachus. Yet Apollonius seems on many occasions to carry further the devices of his master. The astonishing parenthesis at 1. 623 f. is a good example, 52 f, F. Bornmann, Call. Hymnus in Dianam, 1–li). (shrink)

Prefrontal cortex is dysregulated in women with restricting anorexia nervosa . It is not known whether appetitive non-conscious stimuli bias cognitive responses in those with RAN. Thirteen women with RAN and 20 healthy controls completed a dorsolateral PFC working memory task and an anterior cingulate cortex conflict task, while masked subliminal food, aversive and neutral images were presented. During the DLPFC task, accuracy was higher in the RAN compared to the HC group, but superior performance was compromised when subliminal food (...) stimuli were presented: errors positively correlated with self-reported trait anxiety in the RAN group. These effects were not observed in the ACC task. Appetitive activation is intact and anxiogenic in women with RAN, and non-consciously interacts with working memory processes associated with the DLPFC. This interaction mechanism may underlie cognitive inhibition of appetitive processes that are anxiety inducing, in people with AN. (shrink)

Radiation therapy therapists face challenging daily tasks that leave them prone to high attrition and burnout and subsequent deficits in performance. Here, we employed an accelerated alpha-theta neurofeedback protocol that is implementable in a busy medical workplace to test if 12 RTTs could learn the protocol and exhibit behavior and brain performance-related benefits. Following the 3-week protocol, participants showed a decrease in subjective cognitive workload and a decrease in response time during a performance task, as well as a decrease in (...) desynchrony of the alpha electroencephalogram band. Additionally, novel microstate analysis for neurofeedback showed a significant decrease in global field power following neurofeedback. These results suggest that the RTTs successfully learned the protocol and improved in perceived cognitive workload following 3 weeks of neurofeedback. In sum, this study presents promising behavioral improvements as well as brain performance-related evidence of neurophysiological changes following neurofeedback, supporting the feasibility of implementing neurofeedback in a busy workplace and encouraging the further study of neurofeedback as a tool to mitigate burnout. (shrink)

A Treatise of Human Nature opens with ambitious hopes for the science of man, but Hume eventually launches into a series of skeptical arguments that culminates in a report of radical skeptical despair. This essay is a preliminary exploration of how to interpret this surprising development. I first distinguish two kinds of surprise twist: those that are incompatible with some preceding portion of the work, and those that are not. This suggests two corresponding pictures of Hume. On one picture, he (...) believed the skeptical development to be at odds with something in early Treatise; on the other, he took these two portions of Book 1 to be perfectly compatible. After defending the claim that Hume endorsed both of these portions, I sketch two promising interpretations—a “perspectivist,” incompatibilist interpretation and a “post-skeptical,” compatibilist interpretation—and offer some reasons to favor the latter view. (shrink)

Imagine that you are given access to an AI chatbot that compellingly mimics the personality and speech of a deceased loved one. If you start having regular interactions with this “thanabot,” could this new relationship be a continuation of the relationship you had with your loved one? And could a relationship with a thanabot preserve or replicate the value of a close human relationship? To the first question, we argue that a relationship with a thanabot cannot be a true continuation (...) of your relationship with a deceased loved one, though it might support one’s continuing bonds with the dead. To the second question, we argue that, in and of themselves, relationships with thanabots cannot benefit us as much as rewarding and healthy intimate relationships with other humans, though we explain why it is difficult to make reliable comparative generalizations about the instrumental value of these relationships. (shrink)

The interdisciplinary group of authors featured in this focus issue contribute to conversations at the intersection of anthropology and ethics by exploring ethical self‐making and moral experimentation among faith‐based actors in a range of humanitarian settings. Kari Henquinet describes the genealogies of American evangelical humanitarianism by focusing on the ethical self‐formation of early World Vision leaders. Rachel Schneider and Sara Williams each explore practices by which relatively privileged individuals seek to cultivate virtue by engaging with those on the margins, in (...) poor, urban neighborhoods in South Africa, and through packaged tours in Israel/palestine, respectively. Sarah Tobin describes projects of Islamic self‐making among displaced refugee women in Jordan. Although they examine a wide range of subjects and settings, they explore a common set of themes, two of which I discuss here: moral experimentation, and engagements with suffering, poverty, and inequality. (shrink)